Rylan Schaeffer

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22 March 2021

Synapse-specific representation of the identity of overlapping memory engrams

by Abdou, ..., Inokuchi (Science 2018)

Research Questions

Previously, Rashid et al. 2016 and Cai et al. 2016 showed that conditioning close in time result in overlapping engrams, and Yokose et al. 2017 further showed that the overlap in neurons between engrams is responsible for linking the shared experiences. This paper asks and answers:

Experiments

Exp 1

1D

1F

1G

1H

Exp 2

Exp 3

Exp 4

3B

3E

Exp 5

3F

3GH

3I

Exp 6

TODO: maybe finish later. this was a big let down

tags: memory-engrams - lateral-amygdala - auditory-fear-conditioning - conditioned-taste-aversion - optogenetics